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Christian McCaffrey
Christian McCaffrey Goes to locker room Sunday
Sun, Oct 25, 2026, 1:05 PM
McCaffrey (thigh) went to the locker room during Sunday's game in Atlanta, Harrison Rich of the San Francisco Chronicle reports.
Analysis: McCaffrey remained on the sideline for the 49ers' third possession to get his left leg worked on, which seemingly stemmed from a hit he took on a 24-yard catch on the team's first drive. Officially questionable to return due to a thigh injury, he attempted to warm up on San Francisco's bench before jogging to the locker room in the middle of the second quarter. Kaelon Black will be the team's leading runner for as long as McCaffrey is out of the contest.
Christian McCaffrey
Christian McCaffrey Questionable to return Sunday
Sun, Oct 25, 2026, 12:51 PM
McCaffrey (thigh) is questionable to return to Sunday's contest in Atlanta, Jennifer Lee Chan of NBC Sports Bay Area reports.
Analysis: McCaffrey appeared to take a big hit at the end of a 24-yard catch on the 49ers' first drive, but he continued to play through it until the team's third possession, when he stayed on the sideline to get worked on by the training staff. During McCaffrey's absence from the contest, rookie Kaelon Black will be San Francisco's primary running back.
Christian McCaffrey
Christian McCaffrey Exits with apparent leg injury
Sun, Oct 25, 2026, 12:46 PM
McCaffrey was getting his lower left leg worked on during the first half of Sunday's game in Atlanta, Nick Wagoner of ESPN.com reports.
Analysis: McCaffrey took a big hit on the 49ers' first possession of Week 7 action after a 24-yard catch, but he continued to play through it until the team's third drive, when he remained on the sideline to get worked on. For as long as McCaffrey is sidelined, Kaelon Black will be San Francisco's primary RB.
Cleared to face Atlanta
Sun, Oct 25, 2026, 10:56 AM
Stout (shoulder) is active for Sunday's game against the Falcons, Brooke Evans of the 49ers' official site reports.
Analysis: Stout is nursing an AC sprain in his shoulder, but the second-year defensive back has been given the green light to play in Sunday's contest. He has 18 tackles (11 solo), including 0.5 sacks, and one pass defense through the first six games of the regular season.
Christian Kirk
Christian Kirk Activated from injured reserve
Sat, Oct 24, 2026, 3:46 PM
The 49ers activated Kirk (calf) from injured reserve and removed his questionable designation for Sunday's game in Atlanta.
Analysis: Kirk suffered a calf injury in the early stages of training camp in late July and kicked off the season on injured reserve with a designation to return. San Francisco opened his practice window Thursday, Oct. 15, but the team didn't activate him ahead of this past Monday's win against the Commanders. After practicing fully Wednesday through Friday this week, though, he's now in the clear to make his 49ers debut Sunday. With Mike Evans (ribs/Achilles) and Deebo Samuel (hamstring) out for Week 7 and three other wide receivers on IR, Kirk will have a good chance to work as the top WR in a receiving corps that includes healthy options Brandin Cooks, Jordan Watkins and Jacob Cowing.
Sidelined for Week 7
Fri, Oct 23, 2026, 9:27 PM
Wallow (hamstring) has been ruled out for Sunday's game against Atlanta.
Analysis: Both Wallow and Luke Gifford (groin) are unavailable for Sunday's contest, leaving Tatum Bethune as the primary depth option at linebacker behind Jaden Dugger, Fred Warner and Dre Greenlaw. Wallow will have extra rest courtesy of the Week 8 bye, so he could be back for Week 9 against the Raiders on Sunday, Nov. 8.
Won't play against Atlanta
Fri, Oct 23, 2026, 9:20 PM
Gifford (groin) has been ruled out for Sunday's game against the Falcons.
Analysis: Gifford didn't practice during Week 7 prep due to a groin injury he picked up against the Commanders in Week 6. The 49ers have a bye for Week 8, so his next chance to play is Week 9 against the Raiders on Sunday, Nov. 8. Garrett Wallow (hamstring) is also out, so Tatum Bethune is currently the lone depth option at linebacker ahead of Sunday's contest.
Set to suit up
Fri, Oct 23, 2026, 8:19 PM
Williams (knee) does not have any injury designation ahead of Sunday's game against the Falcons.
Analysis: Williams started Week 7 prep as a non-participant but gradually worked his way up to full participation in Friday's session. The defensive end has overcome his knee injury in time to suit up opposite Keion White for Sunday's game.
Questionable for Sunday
Fri, Oct 23, 2026, 8:16 PM
Stout (shoulder) is listed as questionable for Sunday's game against the Falcons.
Analysis: Stout logged consecutive DNPs to begin Week 7 prep before upgrading to a limited participant in Friday's session. The last-minute practice participation has given the cornerback a chance to recover from his AC joint issue in time for Sunday's contest, but it remains uncertain if the 24-year-old will suit up. If Stout cannot play, Ashtyn Davis will likely start at slot cornerback in his place.
Won't play Sunday
Fri, Oct 23, 2026, 8:11 PM
Sigle (ankle) has been ruled out ahead of Sunday's game against the Falcons.
Analysis: Sigle managed to upgrade to a limited participant in Friday's practice after missing consecutive sessions to start Week 7 prep. The strong safety's last-minute upgrade in participation level was not enough to enable him to suit up for Sunday's game, leaving Malik Mustapha as a starter in the 49ers' secondary for a third consecutive week.
Set for Sunday
Fri, Oct 23, 2026, 8:05 PM
Dugger (knee) does not have any injury designation ahead of Sunday's game against the Falcons.
Analysis: Dugger started Week 7 prep with consecutive limited practices before upgrading to a full participant in Friday's session. The strongside linebacker is all set to suit up opposite Dre Greenlaw for Sunday's game against the Falcons.
Jordan Watkins
Jordan Watkins Should have opportunity for larger role
Fri, Oct 23, 2026, 8:05 PM
Watkins could take on a significant role Sunday against Atlanta with Mike Evans (Achilles) and Deebo Samuel (hamstring) both sidelined, Brooke Evans of the 49ers' official site reports.
Analysis: Watkins already saw a big jump in participation this past Monday versus Washington, tallying a season-high 76 percent offensive snap share in Samuel's absence. However, he drew just one target, which he caught for a 22-yard gain. Now that Evans will also be out of action, Watkins seems likely to be deployed often again Sunday, though Brandin Cooks and Jacob Cowing should also get opportunities to step into larger roles. Finally, Christian Kirk (calf), who is currently on IR, may be activated ahead of the matchup versus Atlanta, and he could also factor into the equation in what would be his 49ers debut.
Won't play Sunday
Fri, Oct 23, 2026, 8:03 PM
Bosa (knee) has been ruled out ahead of Sunday's game against the Falcons.
Analysis: Coach Kyle Shanahan stated that Bosa was "a little too optimistic" with his statement that he would be back before the bye, David Lombardi of SFStandard.com reported Friday. The defensive end's chances to play were also diminished because Sunday's game in Atlanta is played on artificial turf. Bosa will continue to recover in anticipation of the 49ers' Week 9 matchup with the Raiders.
Brandin Cooks
Brandin Cooks May take over No. 1 WR role Sunday
Fri, Oct 23, 2026, 7:49 PM
Cooks could be set to work as San Francisco's top wideout Week 7 against Atlanta, as both Mike Evans (Achilles) and Deebo Samuel (hamstring) have been ruled out for the contest, per Brooke Evans of the team's official site.
Analysis: Cooks logged a season-high 52 percent offensive snap share in Monday's win over Washington while Samuel was sidelined, and now Evans is set to miss at least one game as well. Cooks managed just one catch on two targets for 13 yards across his 32 offensive snaps, however, as QB Brock Purdy directed a majority of his 29 passes to tight end George Kittle (eight targets) and running back Christian McCaffrey (10 targets). Kittle and McCaffrey could be looked to often again in Week 7, with Cooks, Jordan Watkins, Jacob Cowing and Christian Kirk (calf) potentially competing for WR targets.
Deebo Samuel Sr.
Deebo Samuel Sr. Officially out this week
Fri, Oct 23, 2026, 4:35 PM
Samuel (hamstring) has been ruled out for Sunday's game at Atlanta, Matt Barrows of The Athletic reports.
Analysis: Samuel was always expected to miss multiple games, with the real question being whether he's ready after a Week 8 bye. He hasn't resumed practicing and will now miss a second straight game, which leaves Jordan Watkins, Brandin Cooks, Jacob Cowing and Christian Kirk (calf) as San Francisco's top WR options in the absence of Mike Evans (out - Achilles).
Christian Kirk
Christian Kirk Listed questionable for Week 7
Fri, Oct 23, 2026, 3:45 PM
Kirk (calf) is questionable for Sunday's game against the Falcons, Matt Barrows of The Athletic reports.
Analysis: Kirk is expected to be activated from injured reserve Saturday, according to David Lombardi of SFStandard.com, paving the way for the veteran wideout to make his 49ers debut Sunday. With Mike Evans (Achilles) and Deebo Samuel (hamstring) ruled out, San Francisco is desperate for healthy bodies at the position. Kirk should immediately slide in for significant snaps alongside Jordan Watkins and Brandin Cooks at wide receiver.
Mike Evans
Mike Evans Ruled out for Week 7
Fri, Oct 23, 2026, 3:37 PM
Evans (Achilles) is out for Sunday's game against the Falcons, Matt Barrows of The Athletic reports.
Analysis: This comes as no surprise after Evans was unable to practice all week following Monday night's early departure against the Commanders. The Niners have a Week 8 bye, and the team hopes Evans will be able to be ready to return following that off week. San Francisco should get Christian Kirk (calf) back from injured reserve this Sunday. He'd join Jordan Watkins and Brandin Cooks atop the depth chart this weekend.
Mike Evans
Mike Evans Not spotted at practice Friday
Fri, Oct 23, 2026, 2:19 PM
Evans (Achilles) wasn't present at the start of Friday's practice, Matt Barrows of The Athletic reports.
Analysis: Evans appears poised to miss every Week 7 practice after he aggravated a right Achilles injury in Monday's win against the Commanders. The 49ers may make a ruling on Evans' availability for Sunday's game in Atlanta once the team posts its final injury report of the week Friday.
Remains sidelined at practice
Thu, Oct 22, 2026, 7:54 PM
Bosa (calf) did not participate at the 49ers' practice Thursday, Nick Wagoner of ESPN.com reports.
Analysis: Bosa was unable to practice for the second straight day to open the week as he continues to work his way back from a calf injury that has sidelined him since Week 2. The defensive lineman is all but guaranteed to miss a fifth straight game Sunday versus the Falcons, but the team expressed optimism that Bosa could return to action Nov. 8 against the Raiders, per Matt Zenitz of CBSSports.com.
Christian Kirk
Christian Kirk Logs another full practice
Thu, Oct 22, 2026, 5:17 PM
Kirk (calf) was a full practice participant Thursday, Nick Wagoner of ESPN.com reports.
Analysis: Back-to-back full practices have Kirk trending in the right direction ahead of Sunday's game against the Falcons. The 49ers have until Saturday to activate Kirk from IR ahead of Week 7 action, but if he's available this weekend he'd provide a boost to a WR corps dealing with injuries to both Mike Evans (ribs/Achilles) and Deebo Samuel (hamstring).

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